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INVESTIGADORES DEL NODO HOSPITAL UNIVERSITARIO SON ESPASES CELEBRAN, JUNTO A LOS PARTICIPANTES DEL ESTUDIO PREDIMED-PLUS, SU ENCUENTRO ANUAL

Los días 9 y 10 de Julio de 2019, tuvo lugar en el Hospital Universitario Son Espases el encuentro anual entre participantes e investigadores del estudio PREDIMED-Plus. Un total de 335 participantes reclutados en centros de salud dependientes del Hospital Son Espases, forman parte de este estudio, que tiene ya una media de seguimiento de 4 años.

Durante el encuentro, pudimos disfrutar de las ponencias del Dr. Miquel Fiol, Investigador Principal del estudio PREDIMED y director científico del IdISBa, así como del Sr. Antoni Colom, dietista-nutricionista. Como invitados especiales, tuvimos a Maria Antònia Puigros y a Pere Berga, expertos en coaching nutricional, que dieron a los participantes indicaciones de cómo mantener la motivación para su participación a largo plazo en el estudio PREDIMED-Plus.

Gracias al apoyo de la empresa Agromart Balear, dedicada a la venta de fruta, verdura y otros productos locales de Baleares, pudimos sortear entre nuestros participantes dos cestas valoradas en 75 euros cada una.

La nota lúdica la puso una banda de música que versionó diversos éxitos musicales de ayer, hoy y siempre, con los que nuestros participantes e investigadores pudieron bailar y disfrutar del buen ambiente y la buena compañía.

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The Jiménez Díaz Foundation honors the volunteers of the PREDIMED-Plus-Madrid Study

The PREDIMED-Plus trial, one of the most important studies carried out to date on the prevention of cardiovascular diseases with a Mediterranean diet, has been honored by the Jiménez Díaz Foundation.

 

Encuentro en el que se ha homenajeado a los autores de Predimed Plus

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Researchers from the University of Toronto visit PREDIMED-Plus

From left to right: Cyril Kendall, Jordi Salas-Salvado and John Sievenpiper

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Dres. Cyril Kendall and John Sievenpiper of the University of Toronto visited the PREDIMED-Plus center of Reus to learn about the difficulties of a large PREDIMED-Plus study. The main objective of the this large trial is to evaluate the effect of an intensive weight loss intervention based on an energy-restricted traditional Mediterranean diet, physical activity promotion and behavioral support on cardiovascular disease (CVD), as compared to a usual. In this visit, the researchers have been observed the field work and they have been interested in the PREDIMED-Plus interventions, the tools used, the logistics and the cost in terms of necessary personnel, facilities and other key aspects of the project.

Reus, December 17, 2018

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THE PREDIMED-PLUS TRIAL AWARDED WITH THE PRIZE PAAS 2018

The study “Effect of a lifestyle intervention program with energy-restricted Mediterranean diet and exercise on weight loss and cardiovascular risk factors: One-year results of the PREDIMED-Plus trial” lead by Prof. Jordi Salas-Salvadó in coordination with 23 Spanish research centers has been recently awarded with The PAAS Prizes within the category of Research.

The PAAS (Plan integral para la promoción de la salud mediante la actividad física y la alimentación saludable) Prizes are made available by the Catalan Public Health Agency with the purpose of identifying, recognizing and disseminating those projects and initiatives which have best contributed to reach the PAAS objectives.

The XI Edition of the PAAS took place on the 26th November 2018 at the Caixa Fórum Auditorium Hall in Barcelona, and the Secretary of the Catalan Public Health Agency gave the Award to Dr. Montse Fitó, Dr. Lluís Serra and Dra. Nancy Babio, who attended in representation of The PREDIMED-Plus research team. The PREDIMED-Plus (Prevención con Dieta Mediterránea) trial is a multicenter, controlled and randomized clinical trial, with parallel groups, conducted in 23 Spanish research centers –5 of which are Catalan–, for the primary prevention of cardiovascular disease through an intensive weight-loss intervention with hypocaloric Mediterranean diet and physical activity promotion, in comparison with a control group, among elder adults with high cardiovascular risk. The total duration of The PREDIMED-Plus trial is 6 years of intervention and 2 additional years of follow-up.

The main objective of this pilot study is to evaluate the effectiveness of the PREDIMED-Plus intervention on body weight and other intermediate cardiovascular risk factors after 12 months in 626 participants out of the 1,013 candidates evaluated for inclusion.

The results from this pilot study, awarded in the PAAS Prizes, have been recently published in the journal Diabetes Care in a publication lead by Prof. Jordi Salas-Salvadó, PI of the Human Nutrition Unit at the Rovira i Virgili University and Principal Investigator at the Pere Virgili Health Research Institute (IISPV) and the CIBEROBN. The study was funded by the Institute of Health Carlos III throuht the Fondo de Investigación para la Salud, a co-found made available by the European Regional Development Fund.

Reference

Salas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, Corella D, Serra-Majem L, Wärnberg J, Romaguera D, Estruch R, Vidal J, Martínez JA, Arós F, Vázquez C, Ros E, Vioque J, López-Miranda J, Bueno-Cavanillas A, Tur JA, Tinahones FJ, Martín V, Lapetra J, Pintó X, Daimiel L, Delgado-Rodríguez M, Matía P, Gómez-Gracia E, Díez-Espino J, Babio N, Castañer O, Sorlí JV, Fiol M, Zulet MÁ, Bulló M, Goday A, Martínez-González MA; PREDIMED-Plus investigators. Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. Diabetes Care. 2018 Nov 2.

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A hypocaloric Mediterranean diet and daily exercise maintain weight loss and improve cardiovascular risk

“The Predimed-Plus trial evaluates more than 600 patients with overweight or obesity and metabolic syndrome, and shows that the health benefits of following this healthier lifestyle are still present after one year

Following a Mediterranean diet low in calories and engaging daily physical activity have proved to reduce body weight and cardiovascular risk in patients with overweight and metabolic syndrome, and to maintain these benefits after one year. These are the main findings of the PREDIMED-Plus (PREvención con DIeta MEDiterránea-Plus) trial, published in the scientific journal Diabetes Care, which have studied more than 600 patients aged between 55 and 75 years old with obesity or overweight and metabolic syndrome. i.e., having three or more of the following cardiovascular risk factors: abdominal obesity, high blood pressure, high blood sugar levels, high triglycerides and low HDL cholesterol.

Nowadays, overweight or obese patients, particularly those with metabolic syndrome, are recommended to lose weight by changing their lifestyle. The aim of these recommendations is to reduce their cardiovascular risk; however, there is no scientific evidence that this beneficial effect can be maintained in the long-term. Although low fat and low carbohydrate diets have proven effective in losing weight and improving cardiovascular risk, the benefits tend to diminish after a year.

With this investigation, the researchers from the Human Nutrition Unit at the Universitat Rovira i Virgili, in collaboration with 23 other research groups in the PREDIMED-Plus study, have evaluated the changes in body weight, fat accumulation and different cardiovascular risk factors after one year in 626 patients. The results have shown that the lifestyle changes included in the study are effective in maintain clinically significant weight loss. Indeed, after 12 months of intervention, 33.7% of the patients following the hypocaloric Mediterranean diet and daily exercise showed a minimum of 5% weight loss. These patients also showed improvements in those parameters related with glucose metabolism and certain inflammatory markers, in contrast with those patients who did not follow the diet. Furthermore, for those patients with diabetes or at risk of diabetes, the benefits from these lifestyle changes were particularly high in terms of glucose control.

The researchers highlight that, in this study, the greatest weight loss has been found after 12 months, which illustrates that weight loss was maintained over time. In the light of these results, the researchers expect that this weight-loss maintenance in response to the PREDIMED-Plus lifestyle programme can provide the same or more benefits that PREDIMED trial for cardiovascular disease (myocardial infarction, stroke or mortality from these causes) in the long term. In fact, this is the main objective of the PREDIMED-PLUS trial.

This study was led by Jordi Salas-Salvadó, head of the Human Nutrition Unit of the Universitat Rovira i Virgili and principal investigator at the Pere Virgili Health Research Institute (IISPV) and CIBERobn. The study was funded by the Carlos III Institute through the Health Research Fund, which is jointly funded by the European Regional Development Fund.

PREDIMED-Plus

The PREDIMED-Plus study, coordinated by Jordi Salas-Salvadó, is a multi-centric clinical trial with a total duration of 8 years and based on a nutritional intervention with hypocaloric Mediterranean diet, the promotion of physical activity and behavioural support for cardiovascular disease prevention. The study is conducted in many different parts of Spain, started in October 2013, and it involves 6,874 individuals.

Reference: Salas-Salvadó J et al. Effect of a lifestyle intervention program with energy-restricted Mediterranean diet and exercise on weight loss and cardiovascular risk factors: One-year results of the PREDIMED-Plus trial. Diabetes Care 2018 Nov; dc180836. doi.org/10.2337/dc18-0836

 

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Article in “Diari de Tarragona”: “Searching for 300 people with obesity to be a part of a nutritional investigation”

See the article in spanish here.